Ceftiofur sodium is a veterinary-specific, semi-synthetic broad-spectrum cephalosporin antibiotic. Like penicillin, it contains a β-lactam ring, classifying it as a β-lactam antibiotic.
Specification
CAS No. : 104010-37-9
EINECS: 680-655-2
Package : 25KG/DRUM
Brand: TOPINCHEM®
Origin: CHINA
Formula: C19H18N5NaO7S3
Minimum Order: 50KG
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Test Items |
Specifications |
Results |
Conclusions |
|
Appearance |
1. White to grayish yellow powder. 2. Odorless, hygroscopic. 3. Dissolve in water. Slightly soluble in propylene glycol, Micro-soluble in methanol. |
Conforms |
Qualified |
|
Identification (HPLC) |
1. In the chromatogram of the record under the determination of content, the retention time of the major peak of the test solution should correspond to the standard. 2. Show the flame reaction of sodium salt. |
Conforms |
Qualified |
|
pH |
5.5~7.5 |
6.4 |
Qualified |
|
Water |
Water content shall not exceed 3.0% |
1.5% |
Qualified |
|
Assay |
Calculated on the anhydrous substance basis, C19H17N5O7S3 shall not be less than 85.0% |
88.0% |
Qualified |
|
Related Substance |
If there are impurity peaks in the chromatogram of the test sample solution, the sum of the impurity peaks' area shall not be greater than 1.5 times(3.0%) of the standard. |
Conforms |
Qualified |
|
Solution Clarity and Color |
I. Shall not be thicker than turbidity standard solution 1. 2 . Shall not be darker than the yellow or orange-yellow standard colorimetric solution 9. |
Conforms |
Qualified |
|
The Residual Solvent of Acetone |
Shall not exceed 2.0% |
1.2% |
Qualified |
|
Bacterial endotoxin |
The amount of endotoxin i every 1mg of Ceftiofur should be less than 0.20EU |
Complies |
Qualified |
Application
Ceftiofur sodium is used in veterinary medicine to treat infections in various animals. It is effective for managing respiratory, gastrointestinal, and systemic infections caused by pathogens typically susceptible to third-generation cephalosporins. It is also used in dogs for urinary tract infections caused by Proteus mirabilis and Escherichia coli.
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