Diclofenac Sodium is a non-steroidal anti-inflammatory drug (NSAID) that primarily works by inhibiting cyclooxygenase (COX), suppressing arachidonic acid metabolism.
Specification
CAS No. : 15307-79-6
EINECS: 239-346-4
Package : 25KG/DRUM
Brand: TOPINCHEM®
Origin: CHINA
Formula: C14H10Cl2NNaO2
Minimum Order: 500KG
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ITEMS |
SPECIFICATION |
RESULTS |
|
Characters |
White to off-white crystalline powder |
White crystalline powder |
|
Melt point |
About 284℃,with decomposition |
Conform |
|
Identification |
A.JR |
Conform |
|
B.HPLC |
Conform |
|
|
C.Test of sodium salt |
Conform |
|
|
Appearance of the solution |
5.0% of methanol solution |
Clear |
|
440nm, NMT 0.05 |
0.009 |
|
|
Clarity of solution |
Equal to methanol |
Conform |
|
pH |
7.0～8.5 |
7.32 |
|
Related substances |
Diclofenac impurity A: NMT0.2% |
Not detected |
|
Any individual impurity: NMT0.2% |
0.05% |
|
|
Total impurities: NMT 0.5% |
0.09% |
|
|
Loss on drying |
NMT 0.5%(lg,105℃,3 hrs) |
0.13% |
|
Assay |
99.0%～101.0% |
99.60% |
Application
Diclofenac sodium is commonly used for managing inflammation, pain, fever, and rheumatic conditions. It is effective in relieving symptoms of musculoskeletal disorders and other inflammatory diseases, with generally tolerable side effects and no reported cumulative toxicity from long-term use.
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