Ivermectin is a novel, broad-spectrum, highly effective, and low-toxicity antibiotic-class antiparasitic drug. As a derivative of avermectin, it is produced through fermentation by Streptomyces avermiltis.
Specification
CAS No. : 70288-86-7
EINECS: 274-536-0
Package : 25KG/DRUM
Brand: TOPINCHEM®
Origin: CHINA
Formula: C48H74O14
Minimum Order: 200KG
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Tests |
Specification |
Result |
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|
Appearance |
White or yellowish-crystalline powder |
White-crystalline powder |
|
|
ldentification |
IR |
Corresponds with that of the CRS standard |
Complies |
|
HPLC |
The retention time for H₂B corresponds with that of the CRS standard |
Complies |
|
|
water |
≤1.0 % |
0.3 |
|
|
Appearance of the solution |
Clear and not more intensely colored than BY? |
Clear |
|
|
Assay(Basis on drying) |
95.0 %～102.0 % |
95.9 |
|
|
H₂B₁/(H₂B₁₄+H₂B₁₀) |
≥90.0 % |
99.6 |
|
|
Related substances |
Individual impurities(RRT1.3-1.5)≤2.5 % |
2.2 |
|
|
Any other individual impurities≤19 |
0.680.170.27 |
||
|
total impurities≤5.0 % |
4.4 |
||
|
Disregard limit≤0.05 % |
0.05 |
||
|
Ethanol |
≤5.0 % |
3.8 |
|
|
Formamide |
≤3.0 % |
2.6 |
|
|
Heavy metal |
≤0.002 % |
<0.001 |
|
|
Sulphated ash |
≤0.1 % |
0.05 |
|
|
Specific optical rotation(anhydrous and solvent-free substance) |
-17°～ -20° |
-18.3° |
|
Application
Ivermectin is widely used in veterinary medicine to control parasitic infections in livestock, poultry, and specialty animals. It is effective against nematodes and ectoparasites in cattle, sheep, swine, and increasingly in reindeer and other exotic species.
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