Storage methods for APIs mainly include the following:
Light-shielding: Use opaque containers, such as brown containers or colorless, transparent, or translucent containers wrapped in black packaging materials. This method is suitable for light-sensitive drugs, such as sodium nitroprusside and insulin drugs.
Light-proof: Avoid direct sunlight. This method is suitable for drugs that are unstable when exposed to light, such as iodine tincture, hydrogen peroxide, and isoniazid drugs.
Sealed: Seal the container to prevent dust and foreign matter from entering. This method is mainly used to prevent dust or foreign matter from entering the container.
Sealed: Seal the container to prevent weathering, moisture absorption, volatilization, or foreign matter from entering. It is suitable for drugs that are hygroscopic or volatile, easily weathered, and easily hydrolyzed when exposed to water, such as ethosuximide and aspirin.
Melt-sealed or tightly sealed: Melt-seal the container or seal it tightly with appropriate materials to prevent the intrusion of air and moisture and prevent contamination. This method is suitable for the packaging of sterile injections, sterile flushing agents and other preparations.
Temperature control: Store according to the sensitivity of the drug to temperature. For example:
Cool place: The temperature does not exceed 20℃. It is suitable for drugs that are more sensitive to temperature, such as beclomethasone dipropionate cream.
Cool and dark place: Avoid light and do not exceed 20℃. It is suitable for drugs that are more sensitive to light and temperature, such as ceftazidime for injection.
Cold place: 2~10℃. It is suitable for drugs that are unstable when exposed to heat, such as tetanus immunoglobulin and hepatitis B immunoglobulin.
Normal temperature: 10~30℃. Unless otherwise specified, the storage temperature of general drugs.
Humidity control: The relative humidity of each warehouse should be maintained between 45%-75% to prevent the drug from getting damp and deteriorating.
